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Volume No. 14(4) 15,December ,2024
Forth Coming Issue
Abstract
The Acalypha genus of plants has been historically utilized in the treatment and management of various health issues, including diabetes, jaundice, hypertension, fever, liver inflammation, schistosomiasis, dysentery, and respiratory disorders such as bronchitis, asthma, and pneumonia. Additionally, these plants are employed in addressing skin conditions like scabies, eczema, and dermatitis. In the present study was aim to phytochemical screening and antimicrobial activity of ethanolic extract of Acalypha fruticosa Forssk leaves. Methods: The plant materials of Acalypha fruticosa Forssk leaves were extracted with ethanol for 3h and collect the extract and screening for identification of phytochemicals and their extract was assessed by antimicrobial activity using the disc diffusion method. The evaluation of antibacterial and antifungal activities involved measuring the diameter (mm) of the inhibition zone surrounding the disc and the assay was conducted three times. The antimicrobial activity was reported as the mean diameters of the leaf extract's inhibition zones of tested bacteria and fungi. Results: The results of the present study were observed that leaf extracts of Acalypha fruticosa Forssk leaves exhibited a maximum concentration of 400mg/ml extract active against maximum inhibited the growth of both tested bacteria and fungi like Salmonella typhi, S. aureus, Candida albicans and Aspergillus niger. The phytochemical constituents of phenolic compounds present in the Acalypha fruticosa leaves possess antibacterial and antifungal properties.
Keywords: Antibacterial activity; Antifungal activity; Acalypha fruticosa Forssk; leaves;phytochemicals